Gabriela Guzman received her B.S. in Bioengineering with high honors from UC Berkeley. Gabriela is currently a Ph.D. candidate in the Department of Bioengineering under the advisement Dr. Bernhard Palsson at UCSD. Her research focuses on utilizing genome-scale models of metabolism and adaptive laboratory evolution to discover ‘underground’ metabolic activities in E. coli. Underground metabolism describes reactions occurring within a cell below the level of detection and is believed to play an important role in evolution. Insights into underground metabolism have direct applications in engineering targeted antibiotics and industrial bioprocessing strains. Her thesis work thus far has been published in PNAS. Gabriela has made international collaborations with laboratories in Russia, Denmark, and Hungary and mentored undergraduate students from the Brazil Scientific Mobility Program. After graduation, Gabriela plans to continue pursuing her academic interests applying systems biology models and sequencing techniques to further explore fundamental biological questions regarding evolutionary mechanisms.